Paul J. Focke is a Ph.D. patent agent with more than six years of law firm experience drafting and prosecuting patents in a wide range of scientific and engineering fields, as well as conducting freedom-to-operate (FTO) analyses and providing written opinions. During this time, Paul has developed a keen understanding of how to protect valuable business assets.

    Prior to joining the firm, Paul worked as a postdoctoral researcher at Oregon Health & Science University (OHSU), where he developed strategies for the engineering and study of clinically important drug targets, including integral membrane protein transporters and ion channels.

    Paul completed his Neuroscience Graduate Program at OHSU, where he developed methodology for studying conformational dynamics of integral membrane protein transporters, following completion of his undergraduate work at the University of Wisconsin – Madison, focusing on molecular biological study and research pursuits.

    During his graduate career, Paul received four different grants, including a National Institutes of Health pre-doctoral National Research Service Award (NRSA) and an American Heart Association postdoctoral award. He has 10 peer-reviewed published articles and numerous published research abstracts. Paul’s Ph.D. education and postdoctoral research experience make him a premier consultant on the patentability of new scientific inventions, providing valuable insight to our healthcare and life sciences clients innovating with new techniques and products.

    Paul received his patent agent certification in September 2020.

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    • Provide consultation on patentability of new inventions, drafting of provisional and non-provisional patent applications, FTO analysis, and prosecution of pending patent applications in a wide range of scientific and engineering fields.


    • Oregon Health and Science University, Doctor of Philosophy, Neuroscience, 2009
    • University of Wisconsin - Madison, Bachelor of Science, Molecular Biology, 1999

    Memberships and Affiliations

    • Post-doctoral fellowship, American Heart Association, July 2012-July 2014
    • Tartar Trust Fellowship, Oregon Health & Science University School of Medicine, July 2009-June 2010
    • National Institutes of Health pre-doctoral NRSA, National Institutes of Neurological Disorders and Stroke, December 2007-November 2009
    • Tartar Trust Fellowship, Oregon Health & Science University School of Medicine, July 2007-June 2008

    • Co-author, “A facile approach for the in vitro assembly of multimeric membrane transport proteins,” Elife, 2018.
    • Co-author, “Combining in vitro folding with cell free protein synthesis for membrane protein expression,” Biochemistry, 2016.
    • Co-author, “Ion-binding properties of a K+ channel selectivity filter in different conformations,” Proc Natl Acad Sci, 2015.
    • Co-author, “Engineering the glutamate transporter GltPh using protein semisynthesis,” Biochemistry, 2015.
    • Co-author, “Neurotransmitter transporters: Structure meets function,” Cell Structure, 2013.
    • Co-author, “Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrate,” Journal of Neuroscience, 2011.
    • Co-author, “Studies of ion channels using expressed protein ligation,” Current Opinion in Chemical Biology, 2010.

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