Nicole Ballew Chang is a patent agent in the Intellectual Property & Technology Practice, with a focus on biotechnology, life sciences and chemical arts. Nicole has experience in molecular and cellular biology, which provides her with distinctive insight into intellectual property challenges for her clients within the scientific industry, including patent drafting, prosecution, and due diligence analysis.

Nicole has extensive experience working directly with researchers at companies to draft and prosecute applications in technologies including coronavirus and cancer vaccines, antibodies, cancer immunotherapies, nutraceuticals and biological bone implants.

Award Mouse thought multimedia interface book medal screen monitor


  • Dartmouth Medical School, Ph.D., 2003
  • Claremont McKenna College, B.A., Cum Laude, 1994


  • U.S. Patent and Trademark Office, 2007

  • Co-author, “Optimization of Humanized IgGs in Glycoengineered Pichia pastoris,” Nature Biotechnol, January 2006.
  • Co-author, “A Rab Requirement is Not Bypassed in SLY1-20 Suppression,” Molecular Biology of the Cell, April 2005.
  • Co-author, “Production of therapeutic proteins in fungal hosts,” Expert Opinion of Biological Therapy, May 2004.
  • Author, “Affinium Pharmaceuticals, Inc: Structure-Guided Drug Discovery,” Chemistry & Biology, May 2004.
  • Author, “Benitec, Ltd. Gene Silencing from Down Under,” Chemistry & Biology, March 2004.
  • Author, “Tools for Nanoscience at McGill University, Sometimes Smaller is Better,” Chemistry & Biology, January 2004.
  • Author, “Cortex Pharmaceuticals, Inc., Maintaining Brain Function Goes a Long Way,” Chemistry & Biology, November 2003.
  • Author, “ImmunoGen, Inc., Immunoconjugates in Cancer Therapy: If At First You Don’t Succeed, Try, Try Again,” Chemistry & Biology, September 2003.
  • Author, “Tethering of COPII Vesicles to the Golgi Complex in Saccharomyces cerevisiae,” Doctoral Thesis, Dartmouth College, June 23, 2003.
  • Author, “Neurocrine Biosciences, Inc., Soporific Science,” Chemistry & Biology, May 2003.
  • Co-author, “Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins,” EMBO J., April 1998.

Award Mouse thought multimedia interface book medal screen monitor